89-021-275
DCTN1, Mouse, Clone: 2E4-1C2, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-021-275-Each-of-1 | In Stock | ₹ 42,898.00 |
89-021-275 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
DCTN1
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC006163
Gene Symbols
DCTN1
Immunogen
DCTN1 (AAH06163, 1 a.a. ∼ 198 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 λ
Applications
ELISA, Western Blot
Clone
2E4-1C2
Description
Mouse monoclonal antibody raised against a full-length recombinant DCTN1.
Gene
DCTN1
Gene Alias
DAP-150/DP-150/HMN7B/P135
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1639
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form
Liquid
Related Products
Description
- This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150kDa
- Dynactin binds to both microtubules and cytoplasmic dynein
- Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis
- This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus
- Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms
- Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA)
- [provided by RefSeq Sequence: MPGPGLVKDSPLLLQQISAMRLHISQLQHENSILKGAQMKASLASLPPLHVAKLSHEGPGSELPAGALYRKTSQLLETLNQLSTHTHVVDITRTSPAAKSPSAQLMEQVAQLKSLSDTVEKLKDEVLKETVSQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGFGQRHRLVLTQEQLHQLHSRLIS