89-021-367
DUSP1, Mouse, Clone: 3A9, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-021-367-Each-of-1 | In Stock | ₹ 47,081.00 |
89-021-367 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,081.00
GST (18%): ₹ 8,474.58
Total Price: ₹ 55,555.58
Antigen
DUSP1
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
NM_004417
Gene Symbols
DUSP1
Immunogen
DUSP1 (NP_004408, 305 a.a. ∼ 367 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2b κ
Applications
ELISA, Immunofluorescence, Western Blot
Clone
3A9
Description
Mouse monoclonal antibody raised against a partial recombinant DUSP1.
Gene
DUSP1
Gene Alias
CL100/HVH1/MKP-1/MKP1/PTPN10
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1843
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form
Liquid
Related Products
Description
- The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors
- It specifies a protein with structural features similar to members of the nonreceptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus
- The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues
- Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes
- Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation
- [provided by RefSeq Sequence: LLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC