89-021-368
DUSP3 (M01), Mouse anti-Human, Clone: 5B7, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-021-368-Each-of-1 | In Stock | ₹ 42,898.00 |
89-021-368 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
DUSP3
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
BC002682
Gene Symbols
DUSP3
Immunogen
DUSP3 (AAH02682, 1 a.a. ∼ 185 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Applications
ELISA, Immunofluorescence, Western Blot
Clone
5B7
Description
Mouse monoclonal antibody raised against a full length recombinant DUSP3.
Gene
DUSP3
Gene Alias
VHR
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1845
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form
Liquid
Related Products
Description
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily
- These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues
- They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation
- Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli
- This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer
- Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1
- [provided by RefSeq Sequence: MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP