89-021-463

EP300, Mouse, Clone: 1B1, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-021-463-Each-of-1 In Stock ₹ 47,704.00

89-021-463 - Each of 1

₹ 47,704.00

In Stock

Quantity

1

Base Price: ₹ 47,704.00

GST (18%): ₹ 8,586.72

Total Price: ₹ 56,290.72

Antigen

EP300

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

PBS with no preservative; pH 7.4

Gene Accession No.

NM_001429

Gene Symbols

EP300

Immunogen

EP300 (NP_001420, 731 a.a. ∼ 830 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Clone

1B1

Description

Mouse monoclonal antibody raised against a partial recombinant EP300.

Gene

EP300

Gene Alias

KAT3B/p300

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2033

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Liquid

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Description

  • This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein
  • It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation
  • It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein
  • This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF
  • Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer
  • [provided by RefSeq Sequence: PPLQHHGQLAQPGALNPPMGYGPRMQQPSNQGQFLPQTQFPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQN