89-022-308
GHR, Mouse, Clone: 3A12, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-022-308-Each-of-1 | In Stock | ₹ 42,898.00 |
89-022-308 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,898.00
GST (18%): ₹ 7,721.64
Total Price: ₹ 50,619.64
Antigen
GHR
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
NM_000163
Gene Symbols
GHR
Immunogen
GHR (NP_000154, 19 a.a. ∼ 118 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a κ
Applications
ELISA, In situ PLA, Western Blot
Clone
3A12
Description
Mouse monoclonal antibody raised against a partial recombinant GHR.
Gene
GHR
Gene Alias
GHBP
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2690
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form
Liquid
Related Products
Description
- This gene encodes a protein that is a transmembrane receptor for growth hormone
- Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth
- A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized
- Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature
- Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized
- In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein
- The precise location of this cleavage site has not been determined for the human protein Sequence: FSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSF