89-024-829
GHR, Mouse, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-024-829-Each-of-1 | In Stock | ₹ 30,794.00 |
89-024-829 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,794.00
GST (18%): ₹ 5,542.92
Total Price: ₹ 36,336.92
Antigen
GHR
Classification
Polyclonal
Description
Mouse polyclonal antibody raised against a partial recombinant GHR.
Gene
GHR
Gene Alias
GHBP
Host Species
Mouse
Purification Method
Unpurified
Regulatory Status
RUO
Gene ID (Entrez)
2690
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Formulation
50% glycerol
Gene Accession No.
NM_000163
Gene Symbols
GHR
Immunogen
GHR (NP_000154, 19 a.a. ∼ 118 a.a) partial recombinant protein with GST tag.
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Related Products
Description
- This gene encodes a protein that is a transmembrane receptor for growth hormone
- Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth
- A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized
- Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature
- Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized
- In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein
- The precise location of this cleavage site has not been determined for the human protein Sequence: FSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSF