89-024-842

GREM1 (C-terminus), Rabbit, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-024-842-Each-of-1 In Stock ₹ 55,981.00

89-024-842 - Each of 1

₹ 55,981.00

In Stock

Quantity

1

Base Price: ₹ 55,981.00

GST (18%): ₹ 10,076.58

Total Price: ₹ 66,057.58

Antigen

GREM1 Ab-1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of GREM1.

Formulation

In PBS (0.09% sodium azide)

Gene Alias

CKTSF1B1/DAND2/DRM/GREMLIN/IHG-2/MGC126660/PIG2

Host Species

Rabbit

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

ELISA, Immunohistochemistry, Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

ELISA (1:1000) Western Blot (1:100-500) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user.

Gene

GREM1

Gene Symbols

GREM1

Immunogen

A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GREM1.

Regulatory Status

RUO

Gene ID (Entrez)

26585

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes a member of the BMP (bone morphogenic protein) antagonist family
  • Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers
  • The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring
  • The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins
  • As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation
  • In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth
  • [provided by RefSeq