89-104-036

ACTN4 (M01A), Mouse anti-Human, Mouse, Rat, Clone: 4D10, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-036-Each-of-1 In Stock ₹ 42,898.00

89-104-036 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

ACTN4

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

ascites with no preservative

Gene Accession No.

NM_004924

Gene Symbols

ACTN4

Immunogen

ACTN4 (NP_004915,592 a.a. ∽ 701 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Regulatory Status

RUO

Gene ID (Entrez)

81

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Ascites

Applications

ELISA, Western Blot

Clone

4D10

Description

Mouse monoclonal antibody raised against a partial recombinant ACTN4.

Gene

ACTN4

Gene Alias

ACTININ-4/DKFZp686K23158/FSGS/FSGS1

Host Species

Mouse

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins
  • Alpha actinin is an actin-binding protein with multiple roles in different cell types
  • In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane
  • In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments
  • This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes
  • Mutations in this gene have been associated with focal and segmental glomerulosclerosis
  • [provided by RefSeq Sequence: KEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYK