89-104-131
AUH, Mouse, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-104-131-Each-of-1 | In Stock | ₹ 30,794.00 |
89-104-131 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,794.00
GST (18%): ₹ 5,542.92
Total Price: ₹ 36,336.92
Antigen
AUH
Classification
Polyclonal
Description
Mouse polyclonal antibody raised against a partial recombinant AUH.
Gene
AUH
Gene Symbols
AUH
Immunogen
AUH (NP_001689, 44 a.a. to 135 a.a) partial recombinant protein with GST tag.
Regulatory Status
RUO
Gene ID (Entrez)
549
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Formulation
50% glycerol
Gene Accession No.
NM_001698
Host Species
Mouse
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Form
Antisera
Related Products
Description
- AU-specific RNA-binding enoyl-CoA hydratase (AUH) protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor
- ARE elements are involved in directing RNA to rapid degradation and deadenylation
- AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity
- AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity
- A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein
- It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein
- Human AUH is expressed as a single mRNA species of 1.8kb, and translated as a 40kDa precursor protein which is subsequently processed to a 32kDa mature form
- [provided by RefSeq] Sequence: RAGPAIWAQGWVPAAGGPAPKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPG