89-104-207

KRIT1, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-207-Each-of-1 In Stock ₹ 30,794.00

89-104-207 - Each of 1

₹ 30,794.00

In Stock

Quantity

1

Base Price: ₹ 30,794.00

GST (18%): ₹ 5,542.92

Total Price: ₹ 36,336.92

Antigen

KRIT1

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant KRIT1.

Gene

KRIT1

Gene Alias

CAM/CCM1

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Antisera

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_004912

Gene Symbols

KRIT1

Immunogen

KRIT1 (NP_004903, 637 a.a. ∽ 736 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

889

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences
  • The encoded protein is localized in the nucleus and cytoplasm
  • It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation
  • It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions
  • It is also a microtubule-associated protein and may play a role in microtubule targeting
  • Mutations in this gene result in cerebral cavernous malformations
  • Multiple alternatively spliced transcript variants have been found for this gene
  • [provided by RefSeq Sequence: AAFFTGQIFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNGQLMPTERNS