89-104-319

CREBL2, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-319-Each-of-1 In Stock ₹ 30,794.00

89-104-319 - Each of 1

₹ 30,794.00

In Stock

Quantity

1

Base Price: ₹ 30,794.00

GST (18%): ₹ 5,542.92

Total Price: ₹ 36,336.92

Antigen

CREBL2

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant CREBL2.

Gene

CREBL2

Gene Alias

MGC117311/MGC138362

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Antisera

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_001310

Gene Symbols

CREBL2

Immunogen

CREBL2 (NP_001301, 31 a.a. to 120 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

1389

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, nonsmall-cell lung and ovarian cancers
  • CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB
  • The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization
  • This suggests that CREBL2 encodes a protein with DNA binding capabilities
  • The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene
  • [provided by RefSeq Sequence: ERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIKALLTGEEQNKSQQNSSRHTKAGKTDANSNSW