89-104-412

E2F3, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-412-Each-of-1 In Stock ₹ 30,794.00

89-104-412 - Each of 1

₹ 30,794.00

In Stock

Quantity

1

Base Price: ₹ 30,794.00

GST (18%): ₹ 5,542.92

Total Price: ₹ 36,336.92

Antigen

E2F3

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length recombinant E2F3.

Gene

E2F3

Gene Alias

DKFZp686C18211/E2F-3/KIAA0075/MGC104598

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Antisera

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

BC016847

Gene Symbols

E2F3

Immunogen

E2F3 (AAH16847, 1 a.a. to 133 a.a) full-length recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

1871

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • The protein encoded by this gene is a member of the E2F family of transcription factors
  • The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses
  • The E2F proteins contain several evolutionally conserved domains found in most members of the family
  • These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain
  • This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain
  • This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner
  • [provided by RefSeq Sequence: MQSGGGVKTDDTSTLNSLCGYAWVYVWEEKQRCRLSSFFSSSASIPGLLPSHTLDLVQNVGVVLDEALGWGRERELCVKCLLEMHCGVFSCMGNHLCQAFPHFPYLSHLVSCLCFQLCVILFASCTKLIFSKV