89-104-497

FKBP4, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-497-Each-of-1 In Stock ₹ 30,794.00

89-104-497 - Each of 1

₹ 30,794.00

In Stock

Quantity

1

Base Price: ₹ 30,794.00

GST (18%): ₹ 5,542.92

Total Price: ₹ 36,336.92

Antigen

FKBP4

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length recombinant FKBP4.

Gene

FKBP4

Gene Alias

FKBP52/FKBP59/HBI/Hsp56/PPIase/p52

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Antisera

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

BC007924.1

Gene Symbols

FKBP4

Immunogen

FKBP4 (AAH07924.1, 1 a.a. to 459 a.a) full-length recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

2288

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking
  • This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin
  • It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506
  • It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes
  • This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase
  • It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors
  • This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines
  • Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy
  • The human genome contains several nontranscribed pseudogenes similar to this gene
  • [provided by RefSeq Sequence: MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA