89-104-590
GRM8, Mouse, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-104-590-Each-of-1 | In Stock | ₹ 30,794.00 |
89-104-590 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,794.00
GST (18%): ₹ 5,542.92
Total Price: ₹ 36,336.92
Antigen
GRM8
Classification
Polyclonal
Description
Mouse polyclonal antibody raised against a partial recombinant GRM8.
Gene
GRM8
Gene Alias
FLJ41058/GLUR8/GPRC1H/MGC126724/MGLUR8/mGlu8
Host Species
Mouse
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Form
Antisera
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Formulation
50% glycerol
Gene Accession No.
NM_000845
Gene Symbols
GRM8
Immunogen
GRM8 (NP_000836, 486 a.a. to 575 a.a) partial recombinant protein with GST tag.
Regulatory Status
RUO
Gene ID (Entrez)
2918
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Description
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors
- Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions
- The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties
- Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C
- Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8
- Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities
- Alternatively spliced transcript variants encoding different isoforms have been described for this gene
- [provided by RefSeq Sequence: KVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPII