89-104-738

IL4R, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-738-Each-of-1 In Stock ₹ 29,459.00

89-104-738 - Each of 1

₹ 29,459.00

In Stock

Quantity

1

Base Price: ₹ 29,459.00

GST (18%): ₹ 5,302.62

Total Price: ₹ 34,761.62

Antigen

IL4R

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant IL4R.

Gene

IL4R

Gene Alias

CD124/IL4RA

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Antisera

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_000418

Gene Symbols

IL4R

Immunogen

IL4R (NP_000409, 26 a.a. ∽ 135 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

3566

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production
  • The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells
  • A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells
  • Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema
  • Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene
  • [provided by RefSeq Sequence: MKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNV