89-104-840

LIG4, Mouse, Clone: 1A4, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-840-Each-of-1 In Stock ₹ 42,898.00

89-104-840 - Each of 1

₹ 42,898.00

In Stock

Quantity

1

Base Price: ₹ 42,898.00

GST (18%): ₹ 7,721.64

Total Price: ₹ 50,619.64

Antigen

LIG4

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

ascites with no preservative

Gene Accession No.

BC037491

Host Species

Mouse

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

Applications

ELISA

Clone

1A4

Description

Mouse monoclonal antibody raised against a partial recombinant LIG4.

Gene

LIG4

Gene Symbols

LIG4

Immunogen

LIG4 (AAH37491,802 a.a. ∽ 911 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Regulatory Status

RUO

Gene ID (Entrez)

3981

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Ascites

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Description

  • The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction
  • This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ)
  • This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK)
  • Both XRCC4 and DNA-PK are known to be required for NHEJ
  • The crystal structure of the complex formed by this protein and XRCC4 has been resolved
  • Defects in this gene are the cause of LIG4 syndrome
  • Alternatively spliced transcript variants encoding the same protein have been observed
  • [provided by RefSeq Sequence: RYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAIKALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDKCELQEENQYLI