89-104-904

MDM2, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-104-904-Each-of-1 In Stock ₹ 30,794.00

89-104-904 - Each of 1

₹ 30,794.00

In Stock

Quantity

1

Base Price: ₹ 30,794.00

GST (18%): ₹ 5,542.92

Total Price: ₹ 36,336.92

Antigen

MDM2

Classification

Polyclonal

Description

Mouse polyclonal antibody raised against a partial recombinant MDM2.

Gene

MDM2

Gene Alias

HDMX/MGC71221/hdm2

Host Species

Mouse

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Antisera

Applications

ELISA

Conjugate

Unconjugated

Formulation

50% glycerol

Gene Accession No.

NM_002392

Gene Symbols

MDM2

Immunogen

MDM2 (NP_002383, 101 a.a. ∽ 200 a.a) partial recombinant protein with GST tag.

Regulatory Status

RUO

Gene ID (Entrez)

4193

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene is a target gene of the transcription factor tumor protein p53
  • The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop
  • Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function
  • This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation
  • This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5
  • More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues
  • [provided by RefSeq Sequence: TMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALC