89-104-914
MAP3K5, Mouse, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-104-914-Each-of-1 | In Stock | ₹ 30,794.00 |
89-104-914 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,794.00
GST (18%): ₹ 5,542.92
Total Price: ₹ 36,336.92
Antigen
MAP3K5
Classification
Polyclonal
Description
Mouse polyclonal antibody raised against a partial recombinant MAP3K5.
Gene
MAP3K5
Gene Alias
ASK1/MAPKKK5/MEKK5
Host Species
Mouse
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human
Form
Antisera
Applications
ELISA, Western Blot
Conjugate
Unconjugated
Formulation
50% glycerol
Gene Accession No.
BC054503
Gene Symbols
MAP3K5
Immunogen
MAP3K5 (AAH54503, 1231 a.a. ∽ 1374 a.a) partial recombinant protein with GST tag.
Regulatory Status
RUO
Gene ID (Entrez)
4217
Content And Storage
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Description
- Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK)
- MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK
- The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells
- MAPKKK5 contains 1374 amino acids with all 11 kinase subdomains
- Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas
- The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK
- [provided by RefSeq Sequence: SHDSQSAHRSLNVQLGRMKIETNRLLEELVRKEKELQALLHRAIEEKDQEIKHLKLKSQPIEIPELPVFHLNSSGTNTEDSELTDWLRVNGADEDTISRFLAEDYTLLDVLYYVTRDDLKCLRLRGGMLCTLWKAIIDFRNKQT