89-105-018

NOTCH3, Mouse, Clone: 1G5, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-105-018-Each-of-1 In Stock ₹ 46,992.00

89-105-018 - Each of 1

₹ 46,992.00

In Stock

Quantity

1

Base Price: ₹ 46,992.00

GST (18%): ₹ 8,458.56

Total Price: ₹ 55,450.56

Antigen

NOTCH3

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

ascites with no preservative

Gene Accession No.

NM_000435

Gene Symbols

NOTCH3

Immunogen

NOTCH3 (NP_000426,47 a.a. ∽ 156 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Regulatory Status

RUO

Gene ID (Entrez)

4854

Content And Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Form

Ascites

Applications

ELISA, Western Blot

Clone

1G5

Description

Mouse monoclonal antibody raised against a partial recombinant NOTCH3.

Gene

NOTCH3

Gene Alias

CADASIL/CASIL

Host Species

Mouse

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a κ

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Description

  • This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch
  • In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development
  • Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined
  • Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
  • [provided by RefSeq Sequence: SPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR