89-109-604

DUX4, Mouse, FITC, Clone: P2B1, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-109-604-Each-of-1 In Stock ₹ 1,22,553.00

89-109-604 - Each of 1

₹ 1,22,553.00

In Stock

Quantity

1

Base Price: ₹ 1,22,553.00

GST (18%): ₹ 22,059.54

Total Price: ₹ 1,44,612.54

Antigen

DUX4

Classification

Monoclonal

Conjugate

FITC

Dilution

Western Blot (1:1000) The optimal working dilution should be determined by the end user.

Gene

DUX4

Gene Symbols

DUX4

Immunogen

Recombinant GST fusion protein corresponding to a 76 amino acid fragment at C-terminus of human DUX4.

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody recognizes human DUX4. It does not cross-react with DUX4c.

Content And Storage

Store at 4°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1

Applications

Immunofluorescence, Immunohistochemistry, Western Blot

Clone

P2B1

Description

Mouse monoclonal antibody raised against recombinant partial DUX4.

Formulation

In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)

Gene Alias

DUX10

Host Species

Mouse

Purification Method

Protein G purification

Regulatory Status

RUO

Gene ID (Entrez)

22947

Target Species

Human

Form

Liquid

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Description

  • This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q
  • The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10
  • Each D4Z4 repeat unit has an open reading frame (named DUX4) that contains two homeoboxes; the repeat-array and ORF is conserved in other mammals
  • There was no evidence for transcription from standard cDNA libraries however RTPCR and in-vitro expression experiments indicate that the ORF is transcribed and the encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307)
  • Contraction of the microsatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD)
  • [provided by RefSeq