89-110-189
CR1, Mouse, Clone: SPM554, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-110-189-Each-of-1 | In Stock | ₹ 68,352.00 |
89-110-189 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 68,352.00
GST (18%): ₹ 12,303.36
Total Price: ₹ 80,655.36
Antigen
CR1
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Immunohistochemistry (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene
CR1
Gene Symbols
CR1
Immunogen
Intact human monocytes.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (PFA fixed), Western Blot
Clone
SPM554
Description
Mouse monoclonal antibody raised against CR1.
Formulation
In 10mM PBS (0.05% BSA, 0.05% sodium azide)
Gene Alias
C3BR/CD35/KN
Host Species
Mouse
Purification Method
Protein A/G purification
Regulatory Status
RUO
Gene ID (Entrez)
1378
Content And Storage
Store at 4°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1 κ
Related Products
Description
- This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1
- The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells
- The Knops blood group system is a system of antigens located on this protein
- The protein mediates cellular binding to particles and immune complexes that have activated complement
- Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis
- Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria
- Alternate allele-specific splice variants, encoding different isoforms, have been characterized
- Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized
- [provided by RefSeq]