89-110-566

CR1, Mouse, Clone: KT23, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-110-566-Each-of-1 In Stock ₹ 68,975.00

89-110-566 - Each of 1

₹ 68,975.00

In Stock

Quantity

1

Base Price: ₹ 68,975.00

GST (18%): ₹ 12,415.50

Total Price: ₹ 81,390.50

Antigen

CR1

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Flow Cytometry (1 ug/100 ul) The optimal working dilution should be determined by the end user.

Gene

CR1

Gene Symbols

CR1

Immunogen

Recombinant protein corresponding to extracellular reagion of human CR1.

Regulatory Status

RUO

Gene ID (Entrez)

1378

Form

Liquid

Applications

Flow Cytometry

Clone

KT23

Description

Mouse monoclonal antibody raised against partial recombinant CR1.

Formulation

In PBS (0.09% sodium azide)

Gene Alias

C3BR/CD35/KN

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1

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Description

  • This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1
  • The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells
  • The Knops blood group system is a system of antigens located on this protein
  • The protein mediates cellular binding to particles and immune complexes that have activated complement
  • Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis
  • Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria
  • Alternate allele-specific splice variants, encoding different isoforms, have been characterized
  • Additional allele specific isoforms, including a secreted form, have been described but have not been fully characterized
  • [provided by RefSeq]