89-110-589
MSR1, Mouse, Clone: SRA-C6, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-110-589-Each-of-1 | In Stock | ₹ 1,22,731.00 |
89-110-589 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,22,731.00
GST (18%): ₹ 22,091.58
Total Price: ₹ 1,44,822.58
Antigen
MSR1
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
Immunohistochemistry (5 ug/mL) Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
Gene
MSR1
Gene Symbols
MSR1
Immunogen
Recombinant protein corresponding to human MSR1.
Regulatory Status
RUO
Gene ID (Entrez)
4481
Form
Liquid
Applications
Immunohistochemistry, Inhibition Assays, Western Blot
Clone
SRA-C6
Description
Mouse monoclonal antibody raised against recombinant MSR1.
Formulation
In PBS (0.1% proclin, 2.0% Block Ace)
Gene Alias
CD204/SCARA1/SR-A/phSR1/phSR2
Host Species
Mouse
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
Related Products
Description
- This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene
- These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense
- The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs)
- The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms
- It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis
- The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages
- [provided by RefSeq]