89-110-661
CASP8, Mouse, Clone: FLICE 1 1-37, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-110-661-Each-of-1 | In Stock | ₹ 84,728.00 |
89-110-661 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 84,728.00
GST (18%): ₹ 15,251.04
Total Price: ₹ 99,979.04
Antigen
CASP8
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
The optimal working dilution should be determined by the end user.
Gene
CASP8
Gene Symbols
CASP8
Immunogen
Recombinant protein corresponding to human CASP8.
Regulatory Status
RUO
Gene ID (Entrez)
841
Form
Liquid
Applications
Western Blot
Clone
FLICE 1 1-37
Description
Mouse monoclonal antibody raised against recombinant CASP8.
Formulation
In PBS (0.08% sodium azide)
Gene Alias
ALPS2B/CAP4/FLICE/FLJ17672/MACH/MCH5/MGC78473
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG
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Description
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family
- Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis
- Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit
- Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits
- This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli
- The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD
- This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases
- Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined
- [provided by RefSeq