APAF1, Rat, Clone: 2E12, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-111-399-Each-of-1 | In Stock | ₹ 1,72,037.00 |
89-111-399 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,72,037.00
GST (18%): ₹ 30,966.66
Total Price: ₹ 2,03,003.66
Antigen
APAF1
Classification
Monoclonal
Conjugate
Unconjugated
Dilution
The optimal working dilution should be determined by the end user.
Gene
APAF1
Gene Symbols
APAF1
Immunogen
Recombinant Flag fusion protein corresponding to amino acids 1-464 of human APAF1.
Regulatory Status
RUO
Gene ID (Entrez)
317
Target Species
Human
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone
2E12
Description
Rat monoclonal antibody raised against partial recombinant APAF1.
Formulation
In PBS (0.02% sodium azide)
Gene Alias
CED4/DKFZp781B1145
Host Species
Rat
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
Recognizes the CARD domain of human Apaf-1. Does not cross-react with mouse or rat Apaf-1.
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG2a
Related Products
Description
- This gene encodes a cytoplasmic protein that initiates apoptosis
- This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC)
- Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome
- The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form
- Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis
- Alternative splicing results in several transcript variants encoding different isoforms
- [provided by RefSeq