89-111-534

INS, Mouse, Clone: 2/5E4, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-111-534-Each-of-1 In Stock ₹ 87,754.00

89-111-534 - Each of 1

₹ 87,754.00

In Stock

Quantity

1

Base Price: ₹ 87,754.00

GST (18%): ₹ 15,795.72

Total Price: ₹ 1,03,549.72

Antigen

INS

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

The optimal working dilution should be determined by the end user.

Gene

INS

Gene Symbols

INS

Immunogen

Recombinant protein corresponding to human INS.

Regulatory Status

RUO

Gene ID (Entrez)

3630

Target Species

Human

Form

Liquid

Applications

ELISA

Clone

2/5E4

Description

Mouse monoclonal antibody raised against recombinant INS.

Formulation

In BBS

Gene Alias

ILPR/IRDN

Host Species

Mouse

Quantity

1 mg

Primary or Secondary

Primary

Test Specificity

This antibody recognizes natural insulin.

Content And Storage

Store at 4°C.

Isotype

IgG1 κ

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Description

  • After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds
  • Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake
  • A variety of mutant alleles with changes in the coding region have been identified
  • There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region
  • [provided by RefSeq]