89-111-556

PRF1, Mouse, Clone: 5B10, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-111-556-Each-of-1 In Stock ₹ 1,90,193.00

89-111-556 - Each of 1

₹ 1,90,193.00

In Stock

Quantity

1

Base Price: ₹ 1,90,193.00

GST (18%): ₹ 34,234.74

Total Price: ₹ 2,24,427.74

Antigen

PRF1

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10) The optimal working dilution should be determined by the end user.

Gene

PRF1

Gene Symbols

PRF1

Immunogen

Recombinant protein corresponding to C-terminus of human PRF1.

Regulatory Status

RUO

Gene ID (Entrez)

5551

Content And Storage

Store at 4°C.

Isotype

IgG1

Applications

Immunohistochemistry, Immunohistochemistry (Frozen)

Clone

5B10

Description

Mouse monoclonal antibody raised against partial recombinant PRF1.

Formulation

In tissue culture supernatant (0.09% sodium azide)

Gene Alias

FLH2/HPLH2/MGC65093/P1/PFN1/PFP

Host Species

Mouse

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • The protein encoded by this gene has structural and functional similarities to complement component 9 (C9)
  • Like C9, this protein creates transmembrane tubules and is capable of lysing nonspecifically a variety of target cells
  • This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis
  • Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood
  • Alternative splicing results in multiple transcript variants encoding the same protein
  • [provided by RefSeq