89-111-595

PLAT, Mouse, Clone: 629-2A153, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-111-595-Each-of-1 In Stock ₹ 1,37,861.00

89-111-595 - Each of 1

₹ 1,37,861.00

In Stock

Quantity

1

Base Price: ₹ 1,37,861.00

GST (18%): ₹ 24,814.98

Total Price: ₹ 1,62,675.98

Antigen

PLAT

Classification

Monoclonal

Conjugate

Unconjugated

Dilution

The optimal working dilution should be determined by the end user.

Gene

PLAT

Gene Symbols

PLAT

Immunogen

Recombinant protein corresponding to human PLAT.

Regulatory Status

RUO

Gene ID (Entrez)

5327

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Clone

629-2A153

Description

Mouse monoclonal antibody raised against recombinant PLAT.

Formulation

In 50mM sodium phosphate buffer, 1mM NaCl, pH 6.6

Gene Alias

DKFZp686I03148/T-PA/TPA

Host Species

Mouse

Quantity

1 mg

Primary or Secondary

Primary

Test Specificity

This epitope is localized to the heavy chain of human tPA and binds well to both the free and complexed form.

Content And Storage

Store at -80°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

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Description

  • This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme
  • Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein
  • This enzyme plays a role in cell migration and tissue remodeling
  • Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism
  • Alternative splicing of this gene results in multiple transcript variants encoding different isoforms
  • [provided by RefSeq