89-111-817

ITGA2B, Mouse, PE, Clone: MEM-06, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-111-817-Each-of-1 In Stock ₹ 54,334.50

89-111-817 - Each of 1

₹ 54,334.50

In Stock

Quantity

1

Base Price: ₹ 54,334.50

GST (18%): ₹ 9,780.21

Total Price: ₹ 64,114.71

Antigen

ITGA2B

Classification

Monoclonal

Conjugate

PE

Dilution

Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106cells in a suspension) The optimal working dilution should be determined by the end user.

Gene

ITGA2B

Gene Symbols

ITGA2B

Immunogen

Native purified ITGA2B from leukocytes of a patient suffering from a LGL-type leukemia.

Regulatory Status

RUO

Gene ID (Entrez)

3674

Target Species

Human

Form

Liquid

Applications

Flow Cytometry

Clone

MEM-06

Description

Mouse monoclonal antibody raised against native ITGA2B.

Formulation

In PBS (0.2% BSA, 0.09% sodium azide)

Gene Alias

CD41/CD41B/GP2B/GPIIb/GTA/HPA3

Host Species

Mouse

Quantity

100 Reactions

Primary or Secondary

Primary

Test Specificity

This antibody reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 KDa) and GPIIb beta (light chain; 23 KDa). CD41 is mainly expressed on platelets and megakaryocytes.

Content And Storage

Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG1

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Description

  • ITGA2B encodes integrin alpha chain 2b
  • Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain
  • Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation
  • Mutations that interfere with this role result in thrombasthenia
  • In addition to adhesion, integrins are known to participate in cell-surface mediated signalling
  • [provided by RefSeq