CD46, Mouse, FITC, Clone: MEM-258, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-111-823-Each-of-1 | In Stock | ₹ 53,133.00 |
89-111-823 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,133.00
GST (18%): ₹ 9,563.94
Total Price: ₹ 62,696.94
Antigen
CD46
Classification
Monoclonal
Conjugate
FITC
Dilution
Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106cells in a suspension) The optimal working dilution should be determined by the end user.
Gene
CD46
Gene Symbols
CD46
Immunogen
Native purified CD46 from human T cell line HPB-ALL.
Regulatory Status
RUO
Gene ID (Entrez)
4179
Target Species
Bovine, Human
Form
Liquid
Applications
Flow Cytometry, Immunoprecipitation, Western Blot
Clone
MEM-258
Description
Mouse monoclonal antibody raised against native CD46.
Formulation
In PBS (0.2% BSA, 0.09% sodium azide)
Gene Alias
MCP/MGC26544/MIC10/TLX/TRA2.10
Host Species
Mouse
Quantity
100 Reactions
Primary or Secondary
Primary
Test Specificity
This antibody recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein). CD46 is 56-66 KDa dimeric transmembrane protein expressed on T and B lymphocytes, platelets, monocytes, granulocytes, endothelial cells, epithelial cells and fibroblast; it is negative on erythrocytes.
Content And Storage
Store in the dark at 4°C. Do not freeze.Avoid prolonged exposure to light.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG1
Related Products
Description
- The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system
- The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement
- In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria
- Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization
- This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system
- At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene
- [provided by RefSeq