89-115-058

SPHK1, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-115-058-Each-of-1 In Stock ₹ 70,399.00

89-115-058 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

SPHK1

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:16000) Western Blot (2-3 ug/mL) The optimal working dilution should be determined by the end user.

Gene

SPHK1

Gene Symbols

SPHK1

Immunogen

A synthetic peptide corresponding to human SPHK1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunoprecipitation, Western Blot

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of SPHK1.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Alias

SPHK

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

8877

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions
  • Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974)
  • Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine
  • Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM Sequence: C-DVDLESEKYRRLGE