89-115-149
DMP1, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-115-149-Each-of-1 | In Stock | ₹ 70,399.00 |
89-115-149 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
DMP1
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:4000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
Gene
DMP1
Gene Alias
DMP-1
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
1758
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of DMP1.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Accession No.
NP_004398.1;NP_001073380.1
Gene Symbols
DMP1
Immunogen
A synthetic peptide corresponding to human DMP1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
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Description
- Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family
- This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues
- The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain
- In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes
- During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation
- Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia
- The gene structure is conserved in mammals
- Two transcript variants encoding different isoforms have been described for this gene
- [provided by RefSeq Sequence: C-ENSEQANTQDSG