89-115-877

ABCG8 Rabbit anti-Human, Mouse, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-115-877-Each-of-1 In Stock ₹ 87,042.00

89-115-877 - Each of 1

₹ 87,042.00

In Stock

Quantity

1

Base Price: ₹ 87,042.00

GST (18%): ₹ 15,667.56

Total Price: ₹ 1,02,709.56

Antigen

ABCG8

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of ABCG8.

Formulation

In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide)

Gene Accession No.

Q9H221

Gene Symbols

ABCG8

Immunogen

A synthetic peptide corresponding to N-terminus of human ABCG8.

Regulatory Status

RUO

Gene ID (Entrez)

64241

Target Species

Human, Mouse

Form

Liquid

Applications

Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:250) The optimal working dilution should be determined by the end user.

Gene

ABCG8

Gene Alias

GBD4/MGC142217/STSL

Host Species

Rabbit

Quantity

200 μL

Primary or Secondary

Primary

Test Specificity

This antibody is specific to human ABCG8.

Content And Storage

Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters
  • ABC proteins transport various molecules across extra- and intra-cellular membranes
  • ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White)
  • This protein is a member of the White subfamily
  • The protein encoded by this gene functions to exclude noncholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen
  • It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder
  • This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5
  • Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia
  • [provided by RefSeq