89-118-418

ACVR1 Rabbit anti-Human, Mouse, Rat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-118-418-Each-of-1 In Stock ₹ 76,718.00

89-118-418 - Each of 1

₹ 76,718.00

In Stock

Quantity

1

Base Price: ₹ 76,718.00

GST (18%): ₹ 13,809.24

Total Price: ₹ 90,527.24

Antigen

ACVR1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of ACVR1.

Formulation

In PBS (0.02% sodium azide)

Gene Accession No.

NP_001096

Gene Symbols

ACVR1

Immunogen

A synthetic peptide corresponding to N-terminus 15 amino acids of human ACVR1.

Regulatory Status

RUO

Gene ID (Entrez)

90

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.

Gene

ACVR1

Gene Alias

ACTRI/ACVR1A/ACVRLK2/ALK2/FOP/SKR1/TSRI

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

Specific of ACVR1C antibody.

Content And Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins
  • Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors
  • These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity
  • Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors
  • Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
  • This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors
  • Mutations in this gene are associated with fibrodysplasia ossificans progressive
  • [provided by RefSeq