89-118-931
UPF3A, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-118-931-Each-of-1 | In Stock | ₹ 53,133.00 |
89-118-931 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,133.00
GST (18%): ₹ 9,563.94
Total Price: ₹ 62,696.94
Antigen
UPF3A
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:8000) The optimal working dilution should be determined by the end user.
Gene
UPF3A
Gene Symbols
UPF3A
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human UPF3A.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody is expected to recognize both isoforms (NP_075387.1; NP_542418.1).
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of UPF3A.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Alias
HUPF3A/RENT3A/UPF3
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
65110
Target Species
Human
Form
Liquid
Related Products
Description
- This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance
- The encoded protein is one of two functional homologs to yeast Upf3p
- mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD)
- When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons
- This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein
- It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions
- This gene is located on the long arm of chromosome 13
- Two splice variants encoding different isoforms have been found for this gene
- [provided by RefSeq Sequence: C-KETDKQKKIAEKE