89-119-661

APAF1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-119-661-Each-of-1 In Stock ₹ 55,892.00

89-119-661 - Each of 1

₹ 55,892.00

In Stock

Quantity

1

Base Price: ₹ 55,892.00

GST (18%): ₹ 10,060.56

Total Price: ₹ 65,952.56

Antigen

APAF1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of APAF1.

Formulation

In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Gene Accession No.

O14727

Gene Symbols

APAF1

Immunogen

A synthetic peptide corresponding to human APAF1.

Regulatory Status

RUO

Gene ID (Entrez)

317

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry, Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:500∼1:1000) Immunohistochemistry (1:50∼1:100) ELISA(1:10000) The optimal working dilution should be determined by the end user.

Gene

APAF1

Gene Alias

CED4/DKFZp781B1145

Host Species

Rabbit

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody is specific to APAF1.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Related Products

Img

Abnova Corporation

89-119-626

--

Img

Abnova Corporation

89-119-660

--

Img

Abnova Corporation

89-119-649

--

Img

Abnova Corporation

89-119-633

--

Img

Abnova Corporation

89-119-646

--

Img

Abnova Corporation

89-119-632

--

Img

Abnova Corporation

89-119-648

--

Img

Abnova Corporation

89-119-307

--

Description

  • This gene encodes a cytoplasmic protein that initiates apoptosis
  • This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC)
  • Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome
  • The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form
  • Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis
  • Alternative splicing results in several transcript variants encoding different isoforms
  • [provided by RefSeq