CYP2D6, Rat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-126-667-Each-of-1 | In Stock | ₹ 70,488.00 |
89-126-667 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,488.00
GST (18%): ₹ 12,687.84
Total Price: ₹ 83,175.84
Antigen
CYP2D6
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
Immunohistochemistry (1:50-1:200) Western Blot (1:500-1:1000) The optimal working dilution should be determined by the end user.
Gene
CYP2D6
Gene Symbols
CYP2D6
Immunogen
A synthetic peptide corresponding to amino acids 241-290 of human CYP2D6.
Quantity
100 μL
Primary or Secondary
Primary
Test Specificity
CYP2D6 polyclonal antibody detects endogenous levels of CYP2D6 protein.
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Description
Rabbit polyclonal antibody raised against synthetic peptide of CYP2D6.
Formulation
In PBS, pH 7.2 (0.05% sodium azide)
Gene Alias
CPD6/CYP2D/CYP2D@/CYP2DL1/MGC120389/MGC120390/P450-DB1/P450C2D/P450DB1
Host Species
Rabbit
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
1565
Target Species
Human
Form
Liquid
Related Products
Description
- This gene encodes a member of the cytochrome P450 superfamily of enzymes
- The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids
- This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs
- Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant
- The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates
- The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1
- Alternatively spliced transcript variants encoding different isoforms have been found for this gene
- [provided by RefSeq]