89-129-096

CMA1, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-129-096-Each-of-1 In Stock ₹ 70,399.00

89-129-096 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

CMA1

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:32000) Western Blot (0.5-2ug/ml) The optimal working dilution should be determined by the end user.

Gene

CMA1

Gene Alias

CYH/MCT1/MGC119890/MGC119891/chymase

Host Species

Goat

Purification Method

Affinity Purified

Regulatory Status

RUO

Gene ID (Entrez)

1215

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

Western Blot

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of CMA1.

Formulation

In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)

Gene Accession No.

NP_001827.1

Gene Symbols

CMA1

Immunogen

A synthetic peptide corresponding to internal region of human CMA1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

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Description

  • This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1
  • It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides
  • In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II
  • Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure
  • Thus, this gene product is a target for cardiovascular disease therapies
  • This gene maps to 14q11.2 in a cluster of genes encoding other proteases
  • [provided by RefSeq Sequence: QFRHPKYNTSTLHHD