89-129-122
RFX5, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-129-122-Each-of-1 | In Stock | ₹ 70,399.00 |
89-129-122 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
RFX5
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:1000) Western Blot (1-3ug/ml) The optimal working dilution should be determined by the end user.
Gene
RFX5
Host Species
Goat
Purification Method
Affinity Purified
Regulatory Status
RUO
Gene ID (Entrez)
5993
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of RFX5.
Formulation
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Gene Symbols
RFX5
Immunogen
A synthetic peptide corresponding to human RFX5.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Canine, Chicken, Human, Mouse, Porcine, Rabbit, Rat
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Description
- A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920)
- At least 4 complementation groups have been identified in B-cell lines established from patients with BLS
- The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters
- The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75kDa subunit of RFX (Steimle et al., 1995)
- RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif
- Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined
- [provided by RefSeq Sequence: TGDKSSEPSTLSNE