89-129-487

PML, Chicken, Biotin, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-129-487-Each-of-1 In Stock ₹ 57,138.00

89-129-487 - Each of 1

₹ 57,138.00

In Stock

Quantity

1

Base Price: ₹ 57,138.00

GST (18%): ₹ 10,284.84

Total Price: ₹ 67,422.84

Antigen

PML

Classification

Polyclonal

Conjugate

Biotin

Formulation

In Phosphate-Buffered Saline with 0.02% Sodium Azide.

Gene Alias

MYL/PP8675/RNF71/TRIM19

Host Species

Chicken

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

5371

Content And Storage

Store at 4°C. For long term storage aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.

Isotype

IgY

Applications

Immuno-MRM (Multiple Reaction Monitoring)

Concentration

1 mg/mL

Description

Chicken polyclonal antibody against synthetic peptide of PML

Gene

PML

Gene Symbols

PML

Immunogen

A Synthetic peptide corresponding to amino acids of PML

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • The protein encoded by this gene is a member of the tripartite motif (TRIM) family
  • The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region
  • This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor
  • Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals
  • The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL)
  • Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus
  • Alternatively spliced transcript variants encoding different isoforms have been identified
  • [provided by RefSeq] Sequence: APASEEEFQFLR