ACTN4, Rabbit, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-130-036-Each-of-1 | In Stock | ₹ 70,488.00 |
89-130-036 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,488.00
GST (18%): ₹ 12,687.84
Total Price: ₹ 83,175.84
Antigen
ACTN4
Classification
Polyclonal
Description
Rabbit polyclonal antibody raised against recombinant ACTN4.
Formulation
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Accession No.
D6PXK4
Gene Symbols
ACTN4
Immunogen
Recombinant protein corresponding to amino acids of human ACTN4.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
Conjugate
Unconjugated
Dilution
Western Blot (1:100-1:500) Immunofluorescence (1-4 ug/ml) Immunohistochemistry (1:1000-1:2500) The optimal working dilution should be determined by the end user.
Gene
ACTN4
Gene Alias
ACTININ-4/DKFZp686K23158/FSGS/FSGS1
Host Species
Rabbit
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
81
Content And Storage
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Isotype
IgG
Related Products
Description
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins
- Alpha actinin is an actin-binding protein with multiple roles in different cell types
- In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane
- In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments
- This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes
- Mutations in this gene have been associated with focal and segmental glomerulosclerosis
- [provided by RefSeq Sequence: MFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANVVGPWIQTKMEEIGRISIEMNGTLE