89-130-103

APEX1 Rabbit anti-Human, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-130-103-Each-of-1 In Stock ₹ 70,488.00

89-130-103 - Each of 1

₹ 70,488.00

In Stock

Quantity

1

Base Price: ₹ 70,488.00

GST (18%): ₹ 12,687.84

Total Price: ₹ 83,175.84

Antigen

APEX1

Classification

Polyclonal

Description

Rabbit polyclonal antibody raised against recombinant APEX1.

Formulation

In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)

Gene Accession No.

G3V3M6

Gene Symbols

APEX1

Immunogen

Recombinant protein corresponding to amino acids of human APEX1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot

Conjugate

Unconjugated

Dilution

Western Blot (1:100-1:250) Immunofluorescence (1-4 ug/ml) Immunohistochemistry (1:200-1:500) The optimal working dilution should be determined by the end user.

Gene

APEX1

Gene Alias

APE/APE-1/APE1/APEN/APEX/APX/HAP1/REF-1/REF1

Host Species

Rabbit

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

328

Content And Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

Isotype

IgG

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Description

  • Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases
  • AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites
  • Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site
  • This gene encodes the major AP endonuclease in human cells
  • Splice variants have been found for this gene; all encode the same protein
  • [provided by RefSeq] Sequence: KLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLAD