89-132-682

CTSF, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-132-682-Each-of-1 In Stock ₹ 70,399.00

89-132-682 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

CTSF

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:32000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene

CTSF

Gene Alias

CATSF

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

8722

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Western Blot

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of CTSF.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Accession No.

NP_003784.2

Gene Symbols

CTSF

Immunogen

A synthetic peptide corresponding to human CTSF.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system
  • Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region
  • The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold
  • The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily
  • This cystatin-like domain contains some of the elements known to be important for inhibitory activity
  • CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide
  • Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway
  • The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W
  • [provided by RefSeq Sequence: CGVNTMASSAVVD