89-132-704

VDR, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-132-704-Each-of-1 In Stock ₹ 70,399.00

89-132-704 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

VDR

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:16000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.

Gene

VDR

Gene Symbols

VDR

Immunogen

A synthetic peptide corresponding to human VDR.

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

Both transcript variants (NP_000367; NP_001017535) encode the same protein.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA, Western Blot

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of VDR.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Alias

NR1I1

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

7421

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • This gene encodes the nuclear hormone receptor for vitamin D3
  • This receptor also functions as a receptor for the secondary bile acid lithocholic acid
  • The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors
  • Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer
  • Mutations in this gene are associated with type II vitamin D-resistant rickets
  • A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream
  • Alternative splicing results in multiple transcript variants encoding the same protein
  • [provided by RefSeq Sequence: CGNQDYKYRVSD