89-132-783
MDM2, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-132-783-Each-of-1 | In Stock | ₹ 70,399.00 |
89-132-783 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
MDM2
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:64000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
Gene
MDM2
Gene Symbols
MDM2
Immunogen
A synthetic peptide corresponding to human MDM2.
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody is expected to recognize isoform MDM2 (NP_002383.2) only.
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of MDM2.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Alias
HDMX/MGC71221/hdm2
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
4193
Target Species
Human
Form
Liquid
Related Products
Description
- This gene is a target gene of the transcription factor tumor protein p53
- The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop
- Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function
- This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation
- This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5
- More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues
- [provided by RefSeq Sequence: C-DELSGERQRKRHKSD