89-132-799

NOTCH3, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-132-799-Each-of-1 In Stock ₹ 70,399.00

89-132-799 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

NOTCH3

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:32000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL) The optimal working dilution should be determined by the end user.

Gene

NOTCH3

Gene Symbols

NOTCH3

Immunogen

A synthetic peptide corresponding to C-terminus of human NOTCH3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Immunohistochemistry (PFA fixed)

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of NOTCH3.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Alias

CADASIL/CASIL

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

4854

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch
  • In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development
  • Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined
  • Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
  • [provided by RefSeq Sequence: C-QLGPQPEVTPKRQ