89-132-860

GNB3 Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-132-860-Each-of-1 In Stock ₹ 70,399.00

89-132-860 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

GNB3

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:1000) The optimal working dilution should be determined by the end user.

Gene

GNB3

Gene Symbols

GNB3

Immunogen

A synthetic peptide corresponding to human GNB3.

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

This antibody is not expected to cross-react with GNB1, 2 and 4.

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

Applications

ELISA

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of GNB3.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Accession No.

NP_002066.1

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

2784

Target Species

Human

Form

Liquid

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Description

  • Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit
  • These subunits are encoded by families of related genes
  • This gene encodes a beta subunit
  • Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors
  • A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity
  • This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity
  • GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites
  • Additional splice variants may exist for this gene, but they have not been fully described
  • [provided by RefSeq Sequence: DCMSLAVSPDFN