ACVR1, Goat, Polyclonal Antibody, Abnova™
Manufacturer: Abnova Corporation
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 89-133-232-Each-of-1 | In Stock | ₹ 70,399.00 |
89-133-232 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 70,399.00
GST (18%): ₹ 12,671.82
Total Price: ₹ 83,070.82
Antigen
ACVR1
Classification
Polyclonal
Conjugate
Unconjugated
Dilution
ELISA (1:128000) Western blot (0.3-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL) The optimal working dilution should be determined by the end user.
Gene
ACVR1
Gene Alias
ACTRI/ACVR1A/ACVRLK2/ALK2/FOP/SKR1/TSRI
Host Species
Goat
Purification Method
Antigen affinity purification
Regulatory Status
RUO
Gene ID (Entrez)
90
Content And Storage
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Applications
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Concentration
0.5 mg/mL
Description
Goat polyclonal antibody raised against synthetic peptide of ACVR1.
Formulation
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene Accession No.
NP_001096.1
Gene Symbols
ACVR1
Immunogen
A synthetic peptide corresponding to human ACVR1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
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Description
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins
- Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors
- These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity
- Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors
- Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors
- This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors
- Mutations in this gene are associated with fibrodysplasia ossificans progressive
- [provided by RefSeq Sequence: C-RKFKRRNQERLNPRD