89-133-263

NRAS, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-133-263-Each-of-1 In Stock ₹ 70,399.00

89-133-263 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

NRAS

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:32000) Western blot (0.01-0.03 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-3 ug/mL) The optimal working dilution should be determined by the end user.

Gene

NRAS

Gene Symbols

NRAS

Immunogen

A synthetic peptide corresponding to internal region of human NRAS.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Form

Liquid

Applications

ELISA, Immunohistochemistry (PFA fixed), Western Blot

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of NRAS.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Alias

ALPS4/N-ras/NRAS1

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

4893

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane
  • This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex
  • The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor
  • Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML)
  • [provided by RefSeq Sequence: C-RMKKLNSSDDGTQ