89-133-399

RAB8A, Goat, Polyclonal Antibody, Abnova™

Manufacturer: Abnova Corporation

Select a Size

Pack Size SKU Availability Price
Each of 1 89-133-399-Each-of-1 In Stock ₹ 70,399.00

89-133-399 - Each of 1

₹ 70,399.00

In Stock

Quantity

1

Base Price: ₹ 70,399.00

GST (18%): ₹ 12,671.82

Total Price: ₹ 83,070.82

Antigen

RAB8A

Classification

Polyclonal

Conjugate

Unconjugated

Dilution

ELISA (1:32000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.

Gene

RAB8A

Gene Symbols

RAB8A

Immunogen

A synthetic peptide corresponding to human RAB8A.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Western Blot

Concentration

0.5 mg/mL

Description

Goat polyclonal antibody raised against synthetic peptide of RAB8A.

Formulation

In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Gene Alias

MEL/RAB8

Host Species

Goat

Purification Method

Antigen affinity purification

Regulatory Status

RUO

Gene ID (Entrez)

4218

Content And Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

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Description

  • The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids
  • The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane
  • This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins
  • The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins
  • However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins
  • Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable
  • This oncogene is located 800kb distal to MY09B on chromosome 19p13.1
  • [provided by RefSeq Sequence: C-NQGVKITPDQQKR